In vitro cytotoxic, genotoxic, and oxidative effects of acyclic sesquiterpene farnesene
نویسندگان
چکیده
Kübra ÇELİK, Başak TOĞAR*, Hasan TÜRKEZ, Numan TAŞPINAR Department of Physiology, Faculty of Medicine, Recep Tayyip Erdoğan University, Rize, Turkey Department of Biology, Faculty of Science, Atatürk University, Erzurum, Turkey Department of Molecular Biology and Genetics, Faculty of Sciences, Erzurum Technical University, Erzurum, Turkey Department of Medical Pharmacology, Medical Faculty, Atatürk University, Erzurum, Turkey
منابع مشابه
In vitro Antioxidant, Cytotoxic, Cholinesterase Inhibitory Activities and Anti-Genotoxic Effects of Hypericum retusum Aucher Flowers, Fruits and Seeds Methanol Extracts in Human Mononuclear Leukocytes
The present study investigates the antioxidant, anticancer, anticholinesterase, anti-genotoxic activities and phenolic contents of flower, fruit and seed methanol extracts of Hypericum retusum AUCHER. The amounts of protocatechuic acid, catechin, caffeic acid and syringic acid in methanol extracts were determined by HPLC. Total phenolic content of H. retusum seed extract was found more than fru...
متن کاملIn vitro Antioxidant, Cytotoxic, Cholinesterase Inhibitory Activities and Anti-Genotoxic Effects of Hypericum retusum Aucher Flowers, Fruits and Seeds Methanol Extracts in Human Mononuclear Leukocytes
The present study investigates the antioxidant, anticancer, anticholinesterase, anti-genotoxic activities and phenolic contents of flower, fruit and seed methanol extracts of Hypericum retusum AUCHER. The amounts of protocatechuic acid, catechin, caffeic acid and syringic acid in methanol extracts were determined by HPLC. Total phenolic content of H. retusum seed extract was found more than fru...
متن کاملIn vitro Valuation of Toxic Effects of Fennel (Foeniculum vulgare Miller.) Seed Decoctions on Plant and Human Cells
The medicinal plants have been used since ancient times and are still utilized by the majority of the population. Hence, it is essential to investigate the cytotoxic and genotoxic effects of these plants. The aim of this study was to evaluate the toxic effects of fennel seeds decoctions, traditionally used in Iran as an herbal remedy. The cytotoxicity was tested in vitro using Allium cepa L. r...
متن کاملIsolation and bacterial expression of a sesquiterpene synthase cDNA clone from peppermint (Mentha x piperita, L.) that produces the aphid alarm pheromone (E)-b-farnesene (insect pheromoneyplant-insect chemical communicationysynomone)
E)-b-Farnesene is a sesquiterpene semiochemical that is used extensively by both plants and insects for communication. This acyclic olefin is found in the essential oil of peppermint (Mentha x piperita) and can be synthesized from farnesyl diphosphate by a cell-free extract of peppermint secretory gland cells. A cDNA from peppermint encoding (E)-b-farnesene synthase was cloned by random sequenc...
متن کاملAmeliorative Effect of Crocin on Sperm Parameters and In Vitro Fertilization in Mice under Oxidative Stress Induced by Paraquat
Objective Background and Objectives: Paraquat (PQ) is a herbicide and is genotoxic and cytotoxic poison for male germ cells. Therefore, in this study, the protective role of Crocin (Cr) against the destructive effects of Paraquat on sperm quality and in-vitro fertilization results Paraquat was investigated. MaterialsAndMethods Materials and Methods: Twenty-eight male mice (20-25g) were used in ...
متن کامل